When Health Secretary Matt Hancock declared that Covid-19 would become “another illness that we have to live with … like flu”, an immediate question arose: what does it mean to learn to live with a new epidemic disease? If, as many experts predict, Covid-19 is not going away any time soon, what can the history of influenza teach us? Dr. Michael Bresalier, Lecturer in the History of Medicine at Swansea University, explores the history of influenza in the 20th century and traces the process by which humanity has adapted to influenza – an ever-changing process and enormous global challenge. He warns that any analogy to Covid-19 must be made with caution.